Searchable abstracts of presentations at key conferences in endocrinology

ea0020p82 | Thyroid | ECE2009

Somatostatin receptor 2 expression in cold thyroid nodules exceeds that of hot thyroid nodules, papillary thyroid carcinoma and Graves’ disease

Sancak Seda , Hardt Anna , Singer Jorg , Kloppel G , Eren Funda Tanay , Sen Leyla Semiha , Gulluoglu Bahadir M , Sever Zeynep , Akalin N Sema , Eszlinger Markus , Paschke Ralf

Objective: The specificity and cellular origin of the SSRS findings in CN, HN, PC and GD is currently unclear and partially contradicts the well defined action of somatostatin on thyroid cell signaling. Therefore, we systematically evaluated SSTR2 expression in benign cold (CN) and hot thyroid nodules (HN), papillary carcinomas (PCs) and GravesÂ’ disease (GD) in comparison with intraindividual control surrounding tissues (ST) by means of immunohistochemistry.<p class="...